Effect of Chrysin on Gentamicin-induced Nephrotoxicity in Laboratory Animals
نویسندگان
چکیده
منابع مشابه
Effect of Chrysin on Gentamicin-induced Nephrotoxicity in Laboratory Animals
Background: Clinically Gentamicin (GM) is commonly used aminoglycoside antibiotic for the treatment of life-threatening Gram-negative bacterial infections, but the nephrotoxic potential of drug limit its clinical interest. Chrysin a plant flavonoid possess potent antioxidant and anti-inflammatory activity. Objective: To investigate the potential of chrysin against GM-induced nephrotoxicity. Mat...
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Objective(s): Gentamicin is used for the treatment of Gram-negative bacterial infections. However, gentamicin administration is limited because of nephrotoxicity. The aim of the present study was to evaluate the protective effect of crocin against gentamicin-induced nephrotoxicity in rats. Materials and Methods: Thirty two male Wistar rats received gentamicin (100 mg/kg, IP), with or without c...
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ژورنال
عنوان ژورنال: Pharmacologia
سال: 2016
ISSN: 2044-4648
DOI: 10.5567/pharmacologia.2016.296.307